Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology
نویسندگان
چکیده
منابع مشابه
P-84: Phospholipase C Zeta: As an Index to Assess Fertilization Potential of a Semen Sample
Background: Failed fertilization post ICSI has been mainly attributed to the sperm’s inability to induce oocyte activation. Phospholipase C Zeta (PLCζ) is considered to be a primary factor for the induction of oocyte activation. The aim of this study was to quantitatively assess the expression of PLCζ in globozoospermic or individuals with previous low or failed fertilization in comparison to f...
متن کاملA maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility.
BACKGROUND Male factor and idiopathic infertility contribute significantly to global infertility, with abnormal testicular gene expression considered to be a major cause. Certain types of male infertility are caused by failure of the sperm to activate the oocyte, a process normally regulated by calcium oscillations, thought to be induced by a sperm-specific phospholipase C, PLCzeta (PLCζ). Prev...
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این پایان نامه بدنبال بررسی کاربرد ارزیابی مستمر در یک محیط یادگیری زبان دوم از طریق طرح چهار سوال تحقیق زیر بود: (1) درک توانایی های فراگیران زمانیکه که از طریق برآورد عملکرد مستقل آنها امکان پذیر نباشد اما در طول جلسات ارزیابی مستمر مشخص شوند; (2) امکان تقویت توانایی های فراگیران از طریق ارزیابی مستمر; (3) سودمندی ارزیابی مستمر در هدایت آموزش فردی به سمتی که به منطقه ی تقریبی رشد افراد حساس ا...
15 صفحه اولDiagnostic Accuracy of Body Mass Index and Fasting Glucose for The Prediction of Gestational Diabetes Mellitus after Assisted Reproductive Technology
Objective Background: To determine maternal pre-pregnancy body mass index (BMI), first trimester fasting blood sugar (FBS) and the combination (BMI+FBS) cut-points for at risk pregnant women conceived by assisted reproduction technology (ART) to better prediction of infertile women’s risk of developing gestational diabetes mellitus (GDM). MaterialsAndMethods In this nested case-control study, 2...
متن کاملI-17: Failed Fertilization: from Molecular,Diagnostic and Clinical Perspectives
Low and/or total failed fertilization following ICSI is a disappointing effect that some couples may face during their treatment which may have severe social and economic consequences for these infertile couples. This phenomenon has been mainly attributed to failed oocyte activation post ICSI. Researchers have regarded this failure due to the absence or deficiency of sperm associated to oocyte ...
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ژورنال
عنوان ژورنال: Cell Communication and Signaling
سال: 2012
ISSN: 1478-811X
DOI: 10.1186/1478-811x-10-12